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Table 2 Deleted region (vGI-20) in vaccine strains IIUK2000 and 2eUK2000

From: Genomic variations associated with attenuation in Mycobacterium avium subsp. paratuberculosisvaccine strains

Gene

Name

Putative function

Process

MAP1694

papA2

Polyketide synthase

Cell Adhesion

MAP1695c

 

Transcriptional regulator

 

MAP1696c

hsp18_1

Heat Shock Protein

Stress protein

MAP1697

 

Transcriptional regulator

 

MAP1698c

hsp18_2

Heat Shock Protein

Stress protein

MAP1699

thil

Thiamine biosynthesis

 

MAP1700c

 

β-lactamase

 

MAP1701c

 

Biotin carboxylase subunit

 

MAP1702c

 

Thioredoxin

 

MAP1703c

 

Unknown

 

MAP1704c

 

Glyoxalase

Anti-host killing factor

MAP1705c

 

Transcriptional regulator

 

MAP1706

 

Chitinase-like protein

 

MAP1707

 

3-ketoacyl-(acp) reductase

Fatty Acid Metabolism

MAP1708

 

Phosphohydrolase-like protein

 

MAP1709

fadD11_2

LuxE like Acyl-protein synthetase

Fatty Acid Metabolism

MAP1710

 

3-oxoadipate enol-lactonase

Fatty Acid Metabolism

MAP1711c

 

Transcriptional regulator

 

MAP1712

 

CoA-transferase family III

 

MAP1713

fadDE20_1

Acyl-CoA dehydrogenase

Fatty Acid Metabolism

MAP1714

fadA_2

Acyl-CoA dehydrogenase

Fatty Acid Metabolism

MAP1715

fadB_2

Acyl-CoA dehydrogenase

Fatty Acid Metabolism

MAP1716

 

Short chain dehydrogenase

Fatty Acid Metabolism

MAP1717

 

Unknown

 

*MAP1718c

 

Low identity to MTB immunogen MPT63

Cell internalization factor

*MAP1719c

 

Transcriptional regulator

 

*MAP1720

 

Nucleoside-diphosphate-sugar epimerases

Cell envelope biosynthesis

*MAP1721c

 

Transcriptional regulator

 

*MAP1722

 

IS900

 

*MAP1723

 

NADP oxidoreductase coenzyme F420-dependent

 

*MAP1724c

 

Cytochrome b N

 

*MAP1725c

 

Catalase

Anti-host killing factor

*MAP1726c

 

Transcriptional regulator

 

*MAP1727

 

Esterase_lipase

Fatty Acid Metabolism

  1. * = MAP specific genes.