Analysis for prevalence and physical linkages amongst integrons, ISEcp1, ISCR1, Tn21 and Tn7 encountered in Escherichia coli strains from hospitalized and non-hospitalized patients in Kenya during a 19-year period (1992–2011)

Table 8 Carriage of aac(6')-lb-cr and qnr genes among strains containing genetic elements and bla genes

		Number (%) of strains carrying each gene and number (%) of strains containing genes linked to genetic elements								Occurrence in strains carryingblagenes^a
	Total	Strains containingintI1	Linked tointI1	Strains containing IS26	Linked to IS26	Strains containing ISCR1	Linked to ISCR1	Strains containing ISEcp1	Linked to ISEcp1	β-lactamase negative strains	Strains containing TEM-1 or SHV-1 only	Strains containing broad-spectru>blagenes
*aac(6’)-lb-cr*	42	42 (100)	42 (100)	6 (14)	4 (9)	12 (29)	6 (14)	11 (26)	4 (10)	0	4 (9)	38 (91)
*qnrA*	34	27 (79)	26 (75)	11 (32)	4 (12)	28 (82)	23 (68)	8 (24)	1 (3)	0	2 (6)	32 (94)
*qnrB*	19	19 (100)	11 (58)	10 (53)	2 (11)	13 (64)	4 (21)	12 (63)	1 (5)	0	1 (5)	18 (95)

Table shows the number of isolates carrying the three (fluoro)quinolone resistance genes and the proportion of such strains in which these genes were physically linked to various genetic elements and to bla genes.
a: Distribution of the aac(6’)-lb-cr and qnr genes among strains fully susceptible to β-lactams, among those resistant to TEM-1 or SHV-1 with a narrow substrate-range and among those carrying genes encoding broad-spectrum β-lactamases such as bla_SHV-5, bla_SHV-12, bla_CMY and bla_CTX-Ms.

ISSN: 1471-2180