Effect of avian influenza A H5N1 infection on the expression of microRNA-141 in human respiratory epithelial cells

Lam, Wai-Yip; Yeung, Apple Chung-Man; Ngai, Karry Lei-Ka; Li, Man-Shan; To, Ka-Fai; Tsui, Stephen Kwok-Wing; Chan, Paul Kay-Sheung

doi:10.1186/1471-2180-13-104

Table 1 miRNAs differentially expressed in H1N1 and H5N1 infected NCI-H292 cells at different time points, respectively

From: Effect of avian influenza A H5N1 infection on the expression of microRNA-141 in human respiratory epithelial cells

A) MiRNAs differentially expressed in cells infected with H1N1 influenza A virus at 3, 6, 18, and 24 hours post-infection, respectively
3-hour	Fold-change	Regulation	6-hour	Fold-change	Regulation	18-hour	Fold-change	Regulation	24-hour	Fold-change	Regulation
hsa-miR-141	1.51	up	hsa-miR-663	1.59	up	hsa-miR-188-5p	1.57	up	hsa-miR-1260	1.58	up
hsa-miR-23a	2	down	hsa-miR-15a*	1.61	down	hsa-miR-1260	1.77	down	hsa-miR-1274a	1.66	up
hsa-miR-574-3p	2.83	down	hsa-miR-1825	1.51	down	hsa-miR-1274a	1.86	down	hsa-miR-1274b	1.91	up
hsa-miR-574-5p	2.99	down	hsa-miR-183*	1.71	down	hsa-miR-1274b	1.69	down	hsa-miR-141	1.51	up
			hsa-miR-34b	1.52	down	hsa-miR-141	1.66	down	hsa-miR-183*	1.54	up
			hsa-miR-494	1.56	down	hsa-miR-17*	1.927	down	hsa-miR-18b	1.64	up
			hsa-miR-574-5p	1.74	down	hsa-miR-21*	1.71	down	hsa-miR-19a	1.52	up
									hsa-miR-21*	1.7	up
									hsa-miR-301a	1.53	up
									hsa-miR-572	1.5	up
									hsa-miR-720	1.99	up
									hsa-miR-939	1.51	up
									hsa-miR-181c*	1.53	down
B) MiRNAs differentially expressed in cells infected with H5N1 influenza A virus at 3, 6, 18, and 24 hours post-infection, respectively.
has-miR-141	1.9	up	hsa-miR-483-3p	3.06	up	hsa-miR-188-5p	2.01	up	hsa-miR-1181	2.6	up
hsa-miR-181c*	1.8	up	hsa-miR-let-7b*	2.02	up	hsa-miR-923	3.39	up	hsa-miR-1207-5p	2.7	up
hsa-miR-210	1.5	up	hsa-miR-126	2.2	down	hsa-miR-1260	3.11	down	hsa-miR-1224-5p	2.02	up
hsa-miR-29b	1.62	up	hsa-miR-20a*	2.42	down	hsa-miR-1274a	3.57	down	hsa-miR-1225-5p	2.44	up
hsa-miR-324-5p	1.759	up	hsa-miR-362-5p	2.6	down	hsa-miR-1274b	4.61	down	hsa-miR-1246	4.39	up
hsa-miR-663	2.01	up	hsa-miR-378	2.16	down	hsa-miR-141	3.2	down	hsa-miR-134	2.78	up
hsa-miR-197	1.64	down	hsa-miR-454	2.32	down	hsa-miR-18a	2.15	down	hsa-miR-188-5p	2.49	up
hsa-miR-339-3p	1.925	down	hsa-miR-574-5p	2.02	down	hsa-miR-18b	3.34	down	hsa-miR-1915	2.84	up
hsa-miR-574-3p	1.77	down				hsa-miR-19a	2.32	down	hsa-miR-572	2.92	up
hsa-miR-574-5p	2.41	down				hsa-miR-21*	3.23	down	hsa-miR-574-3p	3.75	up
						hsa-miR-301a	2.32	down	hsa-miR-574-5p	2.083	up
						hsa-miR-30e	2.24	down	hsa-miR-629*	2.85	up
						hsa-miR-720	3.39	down	hsa-miR-638	2.19	up
									hsa-miR-663	4.52	up
									hsa-miR-939	2.32	up
									hsa-miR-100*	3.47	down
									hsa-miR-1260	3.09	down
									hsa-miR-1280	3.01	down
									hsa-miR-141	4.5	down
									hsa-miR-21*	4	down
									hsa-miR-221	2.72	down
									hsa-miR-455-3p	2.16	down

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ISSN: 1471-2180

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