Figure 2
From: Identification of a novel lipin homologue from the parasitic protozoan Trypanosoma brucei
Amino acid sequence alignment of TbLpn conserved domains and other lipin family members. A) Amino acid sequence alignment of N-LIP domains. Sequences were aligned using CLUSTALW. Identical and conserved amino acids are shown in black and grey boxes, respectively. B) Amino acid sequence alignment of C-LIP domains. Sequences were aligned using CLUSTALW. Identical and conserved amino acids are shown in black and grey boxes, respectively. The conserved aspartic acid residues shown to be essential for enzymatic activity in yeast and mammalian lipins are indicated by asterisks (*).