|
Source
|
Strain
|
Bacteria recovered from blood and tissues (×105 CFU)a
|
|---|
|
4 dpi
|
7 dpib
|
11 dpib
|
|---|
|
Blood
|
SC-19
|
4.49 ± 3.24
|
2.37 ± 1.71
|
0.44 ± 0.04
|
| |
Δ
perR
|
4.10 ± 2.41
|
0.09 ± 0.05
|
0
|
|
Lung
|
SC-19
|
4.22 ± 1.45
|
1.48 ± 0.11
|
1.03 ± 1.59
|
| |
Δ
perR
|
1.66 ± 1.11
|
0.07 ± 0.04
|
0
|
|
Brain
|
SC-19
|
5.07 ± 3.07
|
1.42 ± 0.20
|
1.62 ± 1.33
|
| |
Δ
perR
|
3.84 ± 2.96
|
0.13 ± 0.12
|
0.01 ± 0.01
|
|
Spleen
|
SC-19
|
0.15 ± 0.09
|
0.35 ± 0.11
|
0.03 ± 0.02
|
| |
Δ
perR
|
0.22 ± 0.22
|
0.04 ± 0.04
|
0
|
- a Mean ± standard deviation of 4 independent experiments. Date is expressed as CFU/ml blood, or CFU per tissue.
- bP<0.05 for comparison of SC-19 versus ΔperR CFU at 7 and 11 dpi (student’s t-test).
