Figure 6

Schematic presentation of the PerR regulatory oxidative stress response in S. suis . (A) dpr is repressed by PerR, and derepression of dpr could be induced by H₂O₂. Abundant Dpr stores iron to prevent Fenton reaction. (B) derepression of metQIN is induced by H₂O₂, leading to increasing Met (methionine) and MetO (methionine sulfoxide) uptake. During Met cyclic oxidation and reduction, H₂O₂ can be reduced to H₂O. (C) FeoAB is negatively regulated by PerR. (The broken lines indicate that the regulatory mechanisms were unclear).