Schematic representation of the IncN plasmids R46, N3 and pKOX105. Not to scale. Boxes represent individual genes or groups of genes, described by name or function of the respective gene products. Blocks marked with arrows represent genes unique to each. Crossed over section between N3 and pKOX105 indicates inverted region. Colour scheme: Yellow- core IncN plasmid function, Green - Type 1 restriction system, Red - antibiotic and heavy metal resistance, Blue - mobile elements, Turquoise - hypothetical genes, Pink - Putative metabolic genes.