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Table 2 Mutational events in the inlA gene

From: Polyphasic characterization and genetic relatedness of low-virulence and virulent Listeria monocytogenes isolates

Sequence types (na)

Number of strains and level of virulenceb

Serotype

Genotypic Group

inlA

Location of premature stop codonc

Mutation

Nucleotide

Event

Typesd

31 (n = 8)

4 LV

1/2a

Ib

564

C-to-T transition

189

5

 

4 V

1/2a

 

12

deletion 1 nt

9

4

13 (n = 11)

11 LV

1/2a

Ia

228

C-to-T transition

77

15

193 (n = 8)

8 LV

1/2a

IIIa

13

insertion 1 nt

26

-

196 (n = 1)

1 V

1/2a

 

13

insertion 1 nt

26

-

9 (n = 8)

2 LV; 2 V

1/2c; 3c; 1/2a

IIIb

1636

deletion 1 nt

577

12

 

2 V

1/2c; 3c

 

2053

G-to-A transition

685

11

 

1 V

1/2a

 

1614

C-to-T transition

539

14

6 (n = 2)

1 V

4b

 

2219

deletion 9 nt

-

-

194 (n = 1)

1 V

4b

 

2219

deletion 9 nt

-

-

  1. a Number of strains in the sequence types.
  2. b Number of strains with the inlA event and level of virulence: V (virulent) or LV (low-virulence).
  3. c Numbers represent the amino acid position of each respective premature stop codon in InlA. The deletion of 9 nucleotides for the 2 last ST did not generate any premature stop codon.
  4. d Mutation types according to Van Stelten et al.[17].