Figure 1From: Investigations into genome diversity of Haemophilus influenzae using whole genome sequencing of clinical isolates and laboratory transformantsWhole genome heat map, constructed by Mauve, to achieve pairwise percentage of genome sequence alignment. Pair-wise Mauve alignments were conducted with 60 H. influenzae and H. haemolyticus genome sequences from strains included on a single sequencing flow cell. For each pair-wise comparison the length of the alignment achieved, expressed as the percentage of the total sequence length, was calculated and a distance matrix created. The heat map was created using the R statistical package and shows the clustered genomes determined by the default R heatmap function clustering methods (http://www.r-project.org/). At the top of the figure, an indication of the relatedness between genomes is given. Mauve achieved pairwise genome sequence alignments of between 69.8 and 94.4% across our range of genomes. Strains are listed in the same order on the x and y axes; groupings discussed in the text are indicated along the top axis and the relevant strains are indicated by brackets on the right hand side axis, labelled with a Greek letter.Back to article page