Figure 3

Graphical representation of the complete periplasmic copper homeostasis ensemble in gamma proteobacteria. Each circle represents a seed protein with circle size indicating its relative abundance in the ensemble (CopA circle represents 100%). Proteins are distributed in five groups following the clustering analysis described in Figure 2. Lines indicate elements association within and between clusters (the length of the lines is not informative). Color key: Inner membrane proteins in green, external membrane proteins in blue, periplasmic soluble proteins in red, and CusB in grey.