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Table 1 The characteristics of the rifampicin-resistant S. aureus isolates studied

From: Molecular characterization of rifampicin-resistant Staphylococcus aureus isolates in a Chinese teaching hospital from Anhui, China

MRSA rpoB mutations Number of isolates Mutation frequency % Rifampicin MIC Resistance pattern
Nucleotide mutation Amino acid substitution MIC(mg/L) Number of isolates
TCA/TTA 486Leu/Ser 4 4.5% 4 4 CIP+E+GEN+TET(3)
CIP+E+GEN+TET+CC (1)
CAT/AAT 481His/Asn 1 1.1% 4 1 CIP+E+GEN+TET(1)
CAT/AAT+TTA/TCA 481His/Asn+466Leu/Ser 45 87.5% 32 45 CIP+E+GEN+TET(7)
CIP+E+GEN+TET+CC (35)
CIP+E+GEN+TET+CC+SXT(2)
CIP+E+GEN+TET+CC+SXT+QD(1)
CAT/AAT+TTA/TCA 481His/Asn+466Leu/Ser 14   64 14 CIP+E+GEN+TET+CC (12)
CIP+E+GEN+TET+CC +SXT(2)
CAT/AAT+TTA/TCA 481His/Asn+466Leu/Ser 11   128 11 CIP+E+GEN+TET+CC (8)
CIP+E+GEN+TET+CC +SXT(3)
CAT/AAT+TTA/TCA 481His/Asn+466Leu/Ser 7   256 7 CIP+E+GEN+TET+CC +SXT(7)
CAT/AAT+GCT/GAT 481His/Asn+477Ala/Asp 5 5.7% 64 5 CIP+E+GEN+TET+CC (5)
CAT/AAT+TTA/TCA+GCT/GAT 481His/Asn+466Leu/Ser+477Ala/Asp 1 1.1% 128 1 CIP+E+GEN+TET+CC (1)