Women registering significant variations in total levels of immune-mediators. P, probiotic group; C, control group; W33, 33rd gestational week (black colour); W37, 37th gestational week (grey colour). Identification numbers of women registering significant variations are reported in x-axis. Data are expressed as pg of total immune-mediators per μg of total vaginal proteins (y-axis). The diagrams show means with error bars representing the standard deviations.