TY - JOUR AU - Chen, Yi-Hsing AU - Anderson, Mark AU - Hendrickx, Antoni PA AU - Missiakas, Dominique PY - 2012 DA - 2012/09/25 TI - Characterization of EssB, a protein required for secretion of ESAT-6 like proteins in Staphylococcus aureus JO - BMC Microbiology SP - 219 VL - 12 IS - 1 AB - Staphylococcus aureus secretes EsxA and EsxB, two small polypeptides of the WXG100 family of proteins. Genetic analyses have shown that production and secretion of EsxA and EsxB require an intact ESAT-6 Secretion System (ESS), a cluster of genes that is conserved in many Firmicutes and encompasses esxA and esxB . Here, we characterize EssB, one of the proteins encoded by the ESS cluster. EssB is highly conserved in Gram-positive bacteria and belongs to the Cluster of Orthologous Groups of protein COG4499 with no known function. SN - 1471-2180 UR - https://doi.org/10.1186/1471-2180-12-219 DO - 10.1186/1471-2180-12-219 ID - Chen2012 ER -