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Table 3 Distribution of emm/ T types and resistance genes in S. pyogenes resistant to erythromycin and tetracycline with respect to the overall Spanish GAS population

From: Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994–2006)

emm T No. of isolates/Total erm(B) erm(A) mef(A) msr(D) tet(M) tet(O)
Erythromycin-resistant (n = 276)        
1 1 9/129 1 2 8 8   
2 2 4/41 1 3 4 1   
3 3 1/26 0 0 0 1   
3 3/13 1/5 0 1 0 0   
4 4 116/137 18 39 116 115   
6 6 28/67 2 0 28 28   
11 11 1/24 1 1 1 1   
12 12 19/68 7 5 18 18   
12 NT 1/1 0 1 1 1   
22 12 3/13 0 3 0 2   
28 28 37/78 33 5 28 8   
28 NT 2/2 1 0 1 0   
44 5/27/44 1/20 0 1 1 1   
71 NT 1/1 1 0 0 0   
75 25 43/46 19 32 42 42   
78 11 1/30 1 0 0 0   
81 B3264 1/1 1 1 1 1   
84 25 6/6 5 4 6 6   
88 28 1/1 1 0 0 1   
Total 276/898 92 98 255 234   
Tetracycline-resistant (n = 42)        
6 6 1/67      1 0
11 11 1/24      1 0
22 12 2/13      2 2
31/13 NT 1/1      1 1
33 3/13 1/1      1 0
36 NT 1/1      1 0
50 NT 1/2      1 1
58 NT 1/6      1 0
60 28 4/5      4 1
73 13 2/11      2 2
77 13 1/7      1 0
77 14/49 1/1      1 0
77 28 21/23      11 20
78 11 1/30      1 0
87 28 2/50      2 2
NT NT 1/1      0 1
Total 42/898      31 30
Erythromycin -Tetracycline-resistant (n = 19)       
1 1 1/129 1 0 1 1 1 1
6 6 1/67 1 0 0 0 1 1
11 11 11/24 11 3 3 5 11 3
12 12 1/68 1 1 1 1 1 0
28 28 2/78 2 1 1 0 2 0
77 28 2/23 1 2 2 0 2 2
83 NT 1/1 1 1 1 0 1 0
Total 19/898 18 8 9 7 19 7