Table 3 Distribution of emm/ T types and resistance genes in S. pyogenes resistant to erythromycin and tetracycline with respect to the overall Spanish GAS population
emm | T | No. of isolates/Total | erm(B) | erm(A) | mef(A) | msr(D) | tet(M) | tet(O) |
|---|---|---|---|---|---|---|---|---|
Erythromycin-resistant (n = 276) | ||||||||
1 | 1 | 9/129 | 1 | 2 | 8 | 8 | ||
2 | 2 | 4/41 | 1 | 3 | 4 | 1 | ||
3 | 3 | 1/26 | 0 | 0 | 0 | 1 | ||
3 | 3/13 | 1/5 | 0 | 1 | 0 | 0 | ||
4 | 4 | 116/137 | 18 | 39 | 116 | 115 | ||
6 | 6 | 28/67 | 2 | 0 | 28 | 28 | ||
11 | 11 | 1/24 | 1 | 1 | 1 | 1 | ||
12 | 12 | 19/68 | 7 | 5 | 18 | 18 | ||
12 | NT | 1/1 | 0 | 1 | 1 | 1 | ||
22 | 12 | 3/13 | 0 | 3 | 0 | 2 | ||
28 | 28 | 37/78 | 33 | 5 | 28 | 8 | ||
28 | NT | 2/2 | 1 | 0 | 1 | 0 | ||
44 | 5/27/44 | 1/20 | 0 | 1 | 1 | 1 | ||
71 | NT | 1/1 | 1 | 0 | 0 | 0 | ||
75 | 25 | 43/46 | 19 | 32 | 42 | 42 | ||
78 | 11 | 1/30 | 1 | 0 | 0 | 0 | ||
81 | B3264 | 1/1 | 1 | 1 | 1 | 1 | ||
84 | 25 | 6/6 | 5 | 4 | 6 | 6 | ||
88 | 28 | 1/1 | 1 | 0 | 0 | 1 | ||
Total | 276/898 | 92 | 98 | 255 | 234 | |||
Tetracycline-resistant (n = 42) | ||||||||
6 | 6 | 1/67 | 1 | 0 | ||||
11 | 11 | 1/24 | 1 | 0 | ||||
22 | 12 | 2/13 | 2 | 2 | ||||
31/13 | NT | 1/1 | 1 | 1 | ||||
33 | 3/13 | 1/1 | 1 | 0 | ||||
36 | NT | 1/1 | 1 | 0 | ||||
50 | NT | 1/2 | 1 | 1 | ||||
58 | NT | 1/6 | 1 | 0 | ||||
60 | 28 | 4/5 | 4 | 1 | ||||
73 | 13 | 2/11 | 2 | 2 | ||||
77 | 13 | 1/7 | 1 | 0 | ||||
77 | 14/49 | 1/1 | 1 | 0 | ||||
77 | 28 | 21/23 | 11 | 20 | ||||
78 | 11 | 1/30 | 1 | 0 | ||||
87 | 28 | 2/50 | 2 | 2 | ||||
NT | NT | 1/1 | 0 | 1 | ||||
Total | 42/898 | 31 | 30 | |||||
Erythromycin -Tetracycline-resistant (n = 19) | ||||||||
1 | 1 | 1/129 | 1 | 0 | 1 | 1 | 1 | 1 |
6 | 6 | 1/67 | 1 | 0 | 0 | 0 | 1 | 1 |
11 | 11 | 11/24 | 11 | 3 | 3 | 5 | 11 | 3 |
12 | 12 | 1/68 | 1 | 1 | 1 | 1 | 1 | 0 |
28 | 28 | 2/78 | 2 | 1 | 1 | 0 | 2 | 0 |
77 | 28 | 2/23 | 1 | 2 | 2 | 0 | 2 | 2 |
83 | NT | 1/1 | 1 | 1 | 1 | 0 | 1 | 0 |
Total | 19/898 | 18 | 8 | 9 | 7 | 19 | 7 | |