In silico evolutionary analysis of Helicobacter pylori outer membrane phospholipase A (OMPLA)

BMC Microbiology

Table 2 Positively-selected sites in pldA of Helicobacter pylori

Site	Residue	Probability ω >1	Posterior probability
5	W	0.955*	1.48 ± 0.20
6	L	0.996**	1.52 ± 0.15
21	S	0.830	1.37 ± 0.33
27	I	1.000**	1.52 ± 0.14
34	R	0.576	1.15 ± 0.42
40	I	0.999**	1.52 ± 0.14
50	A	0.989*	1.51 ± 0.15
59	P	0.858	1.39 ± 0.29
137	D	1.000**	1.52 ± 0.14
144	D	0.760	1.32 ± 0.33
153	M	1.000**	1.52 ± 0.14
209	P	0.851	1.39 ± 0.31
211	G	0.836	1.38 ± 0.30
278	V	0.962*	1.48 ± 0.15

PAML predicted that 14 sites were under positive selection (ω >1) using Bayes empirical Bayes analysis for the M8 model. One asterisk (*) signifies a probability >95% that ω >1, while two asterisks (**) signify a probability greater than 99%. The best ancestral reconstruction is indicated by the highest value in the final posterior probability column.

ISSN: 1471-2180