Figure 1

Summary of the microbial phyla and orders detected in interstitial cystitis urine and healthy female urine. A: A comparative taxonomic tree view of 16S rDNA sequences from interstitial cystitis (IC) urine and healthy female (HF) urine assigned to the phylum level as computed using MEGAN V3.4. Normalized counts by pooling together results from V1V2 and V6 16S rDNA sequence datasets were used for both IC and HF urine. B and C: Comparison of taxonomic assignments for IC and HF urine sequences at the order level, showing an increase of the order Lactobacillales in IC urine sequences relative to HF urine, for both V1V2 (B) and V6 datasets (C).