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Figure 3 | BMC Microbiology

Figure 3

From: Bacillus anthracis-derived edema toxin (ET) counter-regulates movement of neutrophils and macromolecules through the endothelial paracellular pathway

Figure 3

ET activates PKA in HMVEC-Ls. HMVEC-Ls were seeded onto 10 cm plates and allowed to reach 80-90% confluence prior to (A) 6 h exposure to increasing doses of ET, or (B) increasing exposure times with ET (1000 ng/mL:1000 ng/mL). Lysates were collected and PKA activity assayed by ELISA. Each vertical bar represents mean (+/- SEM) absorbance at 450 nm. The n for each group is indicated in each bar. * indicates significantly increased compared to the simultaneous medium controls at p < 0.05.

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