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Table 1 Predicted amino acids of adenylation domains in the Plp synthetase

From: Identification and functional analysis of gene cluster involvement in biosynthesis of the cyclic lipopeptide antibiotic pelgipeptin produced by Paenibacillus elgii

A-domain

Amino acid at PheA residuea

Predicted substrate

 

235

236

239

278

299

301

322

330

331

517

 

PlpD A1

D

V

G

E

I

S

A

I

D

K

Dab

PlpE A1

D

G

F

F

L

G

V

V

F

K

Ile

PlpE A2

D

V

G

E

I

S

A

I

D

K

Dab

PlpE A3

D

A

W

T

I

A

A

I

C

K

Phe

PlpE A4

D

A

W

I

I

G

A

I

V

K

Leu

PlpE A5

D

V

G

E

I

S

A

I

D

K

Dab

PlpE A6

D

A

F

W

I

G

G

T

F

K

Val

PlpE A7

D

A

W

I

I

G

A

I

V

K

Leu

PlpF A1

D

V

W

H

F

S

L

V

D

K

Ser

  1. aThe residues were numbered according to the corresponding residues of PheA.
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BMC Microbiology

ISSN: 1471-2180

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