Leptospira spp. strain identification by MALDI TOF MS is an equivalent tool to 16S rRNA gene sequencing and multi locus sequence typing (MLST)

Table 4 Differentiating peaks based on the statistical analysis of ClinProTools within the species L. interrogans and L. kirschneri

genomospecies	peak mass (m/z) representing the protein size in Dalton
genomospecies	3,206	3,220	3,234	3,636	3,657	5,526	6,191	6,327	7,358	8,097
L. interrogans Hebdomadis	-	-	-	-	-	+	+	-	+	-
L. interrogans Australis	-	-	-	-	-	-	+	-	+	-
L. interrogans Autumnalis	-	-	-	-	-	+	+	-	+	-
L. interrogans Bratislava	-	-	-	-	-	+	+	-	+	-
L. interrogans Canicola	-	-	-	-	-	+	+	-	+	-
L. interrogans Copenhageni	-	-	-	++	++	+	+	+	-	-
L. interrogans Hardjo	-	-	-	-	-	+	+	-	+	-
L. interrogans Pomona	++	++	++	-	-	+	+	+	-	-
L. interrogans Pyrogenes	-	-	-	-	-	+	+	-	+	-
L. interrogans Icterohaemorrhagiae	-	-	-	-	-	+	+	+	-	-
L. interrogans Bataviae	-	-	-	-	-	+	+	-	+	-
L. kirschneri Grippotyphosa	-	-	-	-	-	+	-	-	+	+

The displayed peaks are based on visual comparison of the algorithms analysis results of the software. All strains were screened twice using the QuickClassifier (QC)/Different average and SNN algorithms.
The used symbols stand for:
no peak found: -
peak present: +
peak set with high intensity: ++

ISSN: 1471-2180