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Table 1 Ten most up- and 10 most down-regulated genes in AGS cells in response to the infection with the different strains of H. pylori

From: Transcriptional profiling of gastric epithelial cells infected with wild type or arginase-deficient Helicobacter pylori

Β Β 

Raw Signal

Net Signal*

Β Β 

H. pyloristrain

H. pyloristrain

TargetID

NS

WT

rocF-

rocF +

WT

rocF-

rocF +

IL8

130.5

531.8

4021.7

1276.8

401.3

3891.2

1146.3

S100A3

143.6

298.2

1488.3

463

154.6

1344.7

319.4

KRT17

1115.3

2555.1

11710.4

7149.9

1439.8

10595.1

6034.6

LCP1

214.4

351.2

1585.8

568.8

136.8

1371.4

354.4

SERPINB2

116.2

129.1

547.4

235.8

12.9

431.2

119.6

RND1

113.6

171.3

576

195.7

57.7

462.4

82.1

ACTG2

402.8

417.7

1388.5

723.4

14.9

985.7

320.6

SPOCD1

170.4

250.4

748

321.4

80

577.6

151

RASD1

157.5

192.8

563.6

269.5

35.3

406.1

112

PLAUR

450.2

1714

4856.2

1649.2

1263.8

4406

1199

RPP40

2648

1581.3

591.7

2117.1

βˆ’1066.7

βˆ’2056.3

βˆ’530.9

RRS1

596.6

397.5

148.2

477.9

βˆ’199.1

βˆ’448.4

βˆ’118.7

CABC1

1038.4

698.2

254.1

652.8

βˆ’340.2

βˆ’784.3

βˆ’385.6

ZNF239

591.8

389.4

139.8

409.2

βˆ’202.4

βˆ’452

βˆ’182.6

SLC1A3

1269.7

1028.9

364.7

875.9

βˆ’240.8

βˆ’905

βˆ’393.8

SOX2

652.5

373.5

126.3

389.7

βˆ’279

βˆ’526.2

βˆ’262.8

LOC91461

830.4

527.4

160.9

606.7

βˆ’303

βˆ’669.5

βˆ’223.7

FGD3

654.5

384.4

115

262.7

βˆ’270.1

βˆ’539.5

βˆ’391.8

ATF7IP2

1059

662.3

185.1

665.7

βˆ’396.7

βˆ’873.9

βˆ’393.3

DKK1

5514.2

2808.6

264.6

2722.3

βˆ’2705.6

βˆ’5249.6

βˆ’2791.9

  1. *Net signal is obtained by subtracting the raw value from the values obtained in H. pylori-infected AGS cells. NS, Non-infected AGS cells.
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BMC Microbiology

ISSN: 1471-2180

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