Figure 2

Network interactions in AGS cells infected with H. pylori . A. Expanded central node of a network (RelA (p65), NFkB, c-IAP2, NFkBIA, and MUC1) generated using the net gene expression values of the different H. pylori infections of the AGS cells. Green arrow = positive regulation; green icons represent receptor ligands (IL-8, VEGFA); red icons represent transcription factors (NFKB1, STAT3); yellow icon represent generic enzyme (p300). Thicker arrows indicate stronger association. B. Heatmap showing the similarity of the different replicates, using the Log10 ratio of the expression values, as explained in Figure 1. Both Figures were generated using data from four replicate independent experiments.