PKMiner: a database for exploring type II polyketide synthases

BMC Microbiology

Table 3 Type II PKS ARO/CYC domain combinations of aromatic polyketide chemotype

Polyketide Chemotype	Type II PKS domain subfamilies									Uniqueness
	ARO_a	ARO_b	ARO_c	CYC_a	CYC_b	CYC_c	CYC_d	CYC_e	CYC_f
Angucyclines	√	√		√						√
Anthracyclines	√	√				√			√	√
	√	√							√	√
	√	√				√		√		x
	√					√				√
Benzoisochromanequinones	√	√					√			√
		√					√			√
Pentangular polyphenols			√		√					√
			√	√	√					x
Tetracenomycins			√	√	√					x
Tetracyclines/aureolic acids	√	√				√		√		x

For each aromatic polyketide chemotype, this table shows ARO/CYC domain combinations of type II PKS gene clusters. The uniqueness column indicates whether or not type II PKS ARO/CYC domain combinations overlap between aromatic polyketide chemotypes.

ISSN: 1471-2180