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Table 1 Minimal inhibitory concentrations of select antibiotics for two isolates of STEC strain H104:H4, STEC O157:H7, and E. coli ATCC 25922

From: Therapeutic concentrations of antibiotics inhibit Shiga toxin release from enterohemorrhagic E. coli O104:H4 from the 2011 German outbreak

 

E. coli strain

 

O104:H4

O157:H7

ATCC25922

 

Isolate

  
 

P5711

P5765

  

Antibiotic

MIC [mg/l]1

Ciprofloxacin

0.125

0.125

0.064

0.032

Chloramphenicol

4.0

4.0

8.0

6.0

Meropenem

0.047

0.047

0.032

0.032

Gentamicin

2.0

2.0

4.0

6.0

Rifampicin

32.0

32.0

16.0

12.0

Fosfomycin

0.25

0.25

0.094

0.19

  1. 1 Minimal inhibitory concentrations (MIC) were determined as described in Methods. Values depict the respective minimal concentration of a given antibiotic that inhibited the visible growth (E-test, BioMerieux).