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Table 3 Tibiotarsal joint swelling and histological examination of joint tissues

From: Comparative molecular analyses of Borrelia burgdorferi sensu stricto strains B31 and N40D10/E9 and determination of their pathogenicity

Strain Inoculum Right joint diameter (mm) (Avg±SD) Right Tibiotarsus inflammation Right knee/Tibial crest (Tc) inflammation
B31 10 4.07±0.06 -, ±, + -, -, -
102 3.90±0.20 -, ±, + -, -, + (Tc)
103 5.10±0.00 3+, 3+ +, +,
104 4.90±0.00 3+, 3+ +, +
N40 10 4.03±0.15 -, 2+, 3+ -, +, +
102 4.60±0.17 +, 2 to 3+, 3+ +(Tc), +, +
103 4.75±0.07 3+, 3+ +, +,
104 5.00±0.00 3+, 3+ +, +
  1. Joint swelling of each dose was quantitated by average diameter of the right tibiotarsal joint of multiple mice with each dose group. Joint inflammation was scored from “-” (no arthritis) to “+++ (3+)” (severe arthritis) in the tibiotarsus for infected mice at each inoculation dose. Knee or Tibial crest (Tc) inflammation was recorded as “-” (no arthritis) to “+” (arthritis) of each infected mouse.