Phylogeny of K. pneumoniae GGDEF proteins. The phylogenetic reconstruction was done using neighbor-joining with 73 amino acid sequences from K. pneumoniae GGDEF proteins and other bacteria. Nodes with less than 70% support after 1000 bootstrap replicates are indicated with an asterisk. GGDEF proteins from Kp342, MGH78578 and NTUH-K2044 are highlighted in purple. Arrowheads represent the unique GGDEF proteins found in the K. pneumoniae strains (3 genomic and 3 plasmic encoded copies). The scale bar indicates the number of amino acid substitutions per site.