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Table 3 Antibiotic resistance gene profiles of the 21 E. faecium strains

From: Complete genome sequence of Enterococcus faecium strain TX16 and comparative genomic analysis of Enterococcus faecium genomes

Gene cat ermA ermB aad6 aad9 aadE aacA- aphD tetL tetM vanA gyrA b parC c pbp5-Rd
Resistance CHL ERY ERY SPC/ STR SPC/ STR SPC/ STR GEN TET TET VAN CIP CIP AMP
Strains              
1,141,733              
Com12              
Com15              
E980              
TX1330              
1,230,933    X X   X X   X X X X X
1,231,408    X X   X X     X X X
1,231,410    X X   X     X X   X
1,231,501              
1,231,502    X X   X X    X X X X
C68    X X   X X   X   X X X
D344SRFa    X X   X   X X     
TX16 X   X X   X   X X     X
E1039              X
E1071 X   X X X X   X   X    X
E1162         X X     X
E1636          X     X
E1679   X X X X   X    X X X X
TX82    X X   X    X X X X X
TX0133A X   X X   X X   X   X X X
U0317    X X   X X     X X X
  1. aA rifampin- and fusidic acid-resistant derivative of clinical strain E. faecium D344S in which the spontaneous loss of pbp5 and its surrounding region resulted in an ampicillin-susceptible phenotype.
  2. bAmino acid change (E to K/G) in residue 87 or (S to R/Y/I) in residue 83 of GyrA.
  3. cAmino acid change (E to K) in residue 86 or (S to R/I) in residue 82 of ParC.
  4. dConsensus sequence of the pbp5-R allele encoding the low affinity Pbp5-R.
  5. eTC6 was not included in this analysis as it is a transconjugant of C68 and D344SRF, so therefore is not a unique genome.