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Table 1 Colorimetric determination of nitric oxide formation as nitrate and nitrite in sera from infected mice obtained after P.berghei ANKA strain infection and after infection with schizonts harbouring the expressed plasmodial DHS shRNA #176 or plasmodial EIF-5A shRNA #18

From: In vitro and in vivo silencing of plasmodial dhs and eIf-5a genes in a putative, non-canonical RNAi-related pathway

Nitrate and nitrite [μmol/L]

Wild type and transfectants

2200,5

P. berghei ANKA wild type

120

DHS-specific shRNA # 176

109

EIF-5A-specific shRNA # 18

  1. Nitrate and nitrite determination after infection of mice with transgenic schizonts expressing plasmodial DHS and EIF-5A shRNAs.