Antibiotic resistance and molecular epidemiology of Staphylococcus aureusin Nigeria

BMC Microbiology

Table 2 Characterization of MRSA isolates from Nigeria based on antibiotic susceptibility pattern, detection of antibiotic resistance genes, SCCmec typing, spa typing and MLST

Isolate No	Location	Sample or Clinical Diagnosis	Antibiotype	Antibiotic resistance genes	SCCmectype	*spa*type	MLST
09-01730	Ile-Ife	Chronic ulcer	PEN, OXA, GEN, OTE, SXT	mecA, aacA-aphD, tetK	V	t451	8
09-01731	Ile-Ife	Urinary tract infection	PEN, OXA, GEN, OTE	mecA, aacA-aphD, tetM	IV	t008	94 (8-slv)
09-01739	Lagos	Wound infection	PEN, OXA, OTE, CIP, SXT	mecA, tetK	V	t002	5
09-01776	Ibadan	Conjunctivitis	PEN, OXA, OTE, SXT	mecA, tetK	V	t064	8
09-01786	Ibadan	Wound infection	PEN, OXA, GEN, OTE, CIP, SXT, MFL	mecA, aacA-aphD, tetK	V	t064	8
09-01789	Maiduguri	Wound infection	PEN, OXA, GEN, ERY, CLI, OTE, CIP, SXT, MFL	mecA, aacA-aphD, ermA, tetM	III	t037	241
09-01791-1	Maiduguri	Semen (Infertility)	PEN, OXA, GEN, ERY, CLI, OTE, CIP, SXT, MFL	mecA, aacA-aphD, ermA, tetM	III^a	t037	241
09-01795	Maiduguri	Throat Infection	PEN, OXA, GEN, ERY, CLI, OTE, CIP, SXT, MFL	mecA, aacA-aphD, ermA, tetM	III^a	t037	ND
09-01809	Maiduguri	Semen (Infertility)	PEN, OXA, GEN, ERY, CLI, OTE, CIP, SXT, MFL	mecA, aacA-aphD, ermA, tetM	III^a	t037	241
09-01811	Maiduguri	Wound Infection	PEN, OXA, GEN, ERY, CLI, OTE, CIP, SXT, MFL	mecA, aacA-aphD, ermA, tetM	III^a	t037	ND
09-01812	Maiduguri	Wound Infection	PEN, OXA, GEN, ERY, CLI, OTE, CIP, SXT, MFL	mecA, aacA-aphD, ermA, tetM	III^a	t037	ND

^aSCCmec type inferred from related isolate 09-01789
slv: single locus variant
Geographical region: South-West Nigeria (Ile-Ife, Ibadan and Lagos)
North-East Nigeria (Maiduguri)
KEY
PEN: Penicillin G; OX: Oxacillin; GEN: Gentamicin; ERY: Erythromycin; CLI: Clindamycin; OTE: Tetracycline; CIP: Ciprofloxacin; SXT: Trimethoprim/sulfamethoxazole; MFL: Moxifloxacin
ND: Not determined

ISSN: 1471-2180