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Table 2 Comparison of bacterial composition from inflamed and non-inflamed tissue within individual IBD patients using ∫-LIBSHUFF, unweighted and weighted UniFrac, the parsimony P-test and RDP Library Compare.

From: High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease

  Crohn's Disease Patients Ulcerative Colitis Patients
  CD1 CD2 CD3 CD4 CD5 CD6 UC1 UC2 UC3 UC4 UC5 UC6
∫-LIBSHUFF * ** ** n/s * n/s * * *** ** * **
UW UniFrac *** *** *** n/s *** *** *** *** ** *** *** ***
W UniFrac ** *** n/s *** * n/s n/s *** *** ** n/s *
P-Test *** *** *** *** *** *** *** *** *** *** *** ***
Library Compare
Firmicutes ↑** ↑***   ↓***      ↑***    
>Clostridiales   ↑***   ↓***      ↑***    
>>Lachnospiraceae   ↑***   ↓***         
>>Ruminococcaceae           ↓**   
Bacteroidetes ↓** ↓***   ↑***      ↓***    
>>>Bacteroides   ↓***           
>>>Parabacteroides ↓**            
>>>Prevotella     ↑***     ↑*** ↓***    
Actinobacteria           ↑**   
>>>Collinsella           ↑**   
Proteobacteria     ↓***         
>>>Sutterella     ↓***         
Fusobacteria      ↑*        
>>>Fusobacterium      ↑*        
  1. Key:- *** = P < 0.001, ** = P < 0.01, * = P < 0.05, n/s = P > 0.05. ↑ = Increased in inflamed vs. non-inflamed tissue, ↓ = Decreased in inflamed vs. non-inflamed tissue. Bold = Phylum level classification, > = Order level classification, >> = Family level classification, >>> = Genus level classification.