Multiple sequence alignment of mutacin F-59.1 with homologous class IIa bacteriocins. Consensus sequence appears in bold. Some of the leader sequences are shown with the double glycine motif. Underneath appears in italic the predicted secondary structure for mutacin F-59.1 and pediocin PA-1. Output classification is as follows: H, alpha-helix; E, extended strand; T, turn; C, the rest . Accession numbers refer to bacteriocins in the protein database from the NCBI (AAC60413, ; AAB23877, ; AAG28763, ; AAL09346, ; P35618, ; P80953, ; ACD01989, ; BAB88211, ; AAQ95741, ).