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Table 4 Accuracy of final DGGE model* in predicting API status at age 3 years

From: Denaturing gradient gel electrophoresis of neonatal intestinal microbiota in relation to the development of asthma

  API index   N  
  Pos Neg   
DGGE model Pos. 13 19 32 PPV = 41%
DGGE model Neg. 11 67 78 NPV = 86%
Total 24 86 110  
  54% S 78% Sp   X2, p = 0.002
  1. Overall correct classification: 80/110 = 73%
  2. API prevalence: 24/110 = 22%
  3. Final DGGE model:
  4. Positive: presence of band 60.1 (Clostridium coccoides subcluster XIVa) or band 45.9 (Bacteroides fragilis subgroup)
  5. Negative: absence of band 60.1 (Clostridium coccoides subcluster XIVa) and band 45.9 (Bacteroides fragilis subgroup)
  6. N: number of cases
  7. PPV: positive predictive value
  8. NPV: negative predictive value
  9. S: sensitivity
  10. Sp: specificity