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Figure 1 | BMC Microbiology

Figure 1

From: The SspA subtilisin-like protease of Streptococcus suis triggers a pro-inflammatory response in macrophages through a non-proteolytic mechanism

Figure 1

Cytokine secretion by PMA-differentiated U937 macrophages stimulated with the recombinant SspA of S. suis or with pancreatic trypsin. Following stimulation (18 h) with various amounts of proteases, the secretion of IL-1β (panel A), IL-6 (panel B), TNF-α (panel C), CXCL8 (panel D) and CCL5 (panel E) was assessed by ELISA. The data are the means ± SD of triplicate assays from three separate experiments. Asterisks indicate a significant difference in comparison with the non-stimulated macrophages at P < 0.01.

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