Table 5 Virulence of S. Typhimurium rec mutants in BALB/c mice (oral inoculation)
From: Improving Salmonella vector with recmutation to stabilize the DNA cargoes
Strain | recdeletion | Dose (CFU) | Survivor/total | LD50 (CFU) |
|---|---|---|---|---|
χ3761 | None | 1.5 × 106 | 0/4 | 3.2 × 104 |
|  |  | 1.5 × 105 | 1/4 |  |
|  |  | 1.5 × 104 | 3/4 |  |
|  |  | 1.5 × 103 | 4/4 |  |
χ9070 | ΔrecF126 | 1.0 × 107 | 0/4 | 6.8 × 104 |
|  |  | 1.0 × 106 | 1/4 |  |
|  |  | 1.0 × 105 | 1/4 |  |
|  |  | 1.0 × 104 | 4/4 |  |
χ9072 | ΔrecJ1315 | 1.0 × 107 | 0/4 | 1.5 × 105 |
|  |  | 1.0 × 106 | 0/4 |  |
|  |  | 1.0 × 105 | 3/4 |  |
|  |  | 1.0 × 104 | 3/4 |  |
χ9081 | ΔrecJ1315 Δ recF126 | 1.0 × 107 | 1/4 | 2.2 × 106 |
|  |  | 1.0 × 106 | 3/4 |  |
|  |  | 1.0 × 105 | 4/4 |  |
|  |  | 1.0 × 104 | 3/4 |  |
χ9833 | ΔrecA62 | 1.3 × 109 | 10/10 | >1.3 × 109 |