Table 1 Candida isolates used in this study and their susceptibility to antifungals and interactions with G. mellonella

C. albicans

4S

Saliva

0.125

0.25

7.1 × 10⁵

16/16

18

10S

Saliva

0.125

0.5

5.2 × 10⁵

16/16

18

24S

Saliva

0.125

0.5

9.4 × 10⁵

16/16

18

31S

Saliva

0.125

0.5

5.0 × 10⁵

16/16

24

39S

Saliva

Resistant

0.25

5.9 × 10⁵

16/16

18

48S

Saliva

0.125

0.25

6.7 × 10⁵

16/16

18

60S

Saliva

0.125

0.25

6.3 × 10⁵

16/16

18

3

OPC

0.5

0.25

7.2 × 10⁵

16/16

18

14

OPC

Resistant

0.25

5.7 × 10⁵

16/16

18

21

OPC

Resistant

0.25

7.5 × 10⁵

16/16

18

37

OPC

Resistant

0.25

5.5 × 10⁵

16/16

18

CAL006

Blood culture

0.125

0.5

1.9 × 10⁵

16/16

24

CAL007

Peritoneal fluid

2

0.25

4.5 × 10⁵

16/16

24

CAL008

Peritoneal fluid

1

0.5

7.2 × 10⁵

16/16

18

CAL009

Blood culture

1

0.5

4.7 × 10⁵

16/16

18

CAL010

Subdiaphragnatic

1

0.5

4.8 × 10⁵

16/16

18

C. tropicalis

12

OPC

0.5

0.25

3.9 × 10⁵

16/16

18

140S

Saliva

0.125

0.25

4.9 × 10⁵

16/16

18

CTR002

Synovial fluid

Resistant

0.5

9.1 × 10⁵

16/16

18

CTR003

Abdominal fluid

2

0.5

5.0 × 10⁵

16/16

18

127S

Saliva

1

0.5

6.2 × 10⁵

16/16

18

CPA001

Lung tissue

4

0.5

7.3 × 10⁵

16/16

21

C. glabrata

12S

Saliva

2

0.5

6.4 × 10⁵

2/16

-

45

OPC

4

0.5

9.8 × 10⁵

6/16

-

55

OPC

4

0.5

1.0 × 10⁶

0/16

-

CGL002

Drainage

32

0.5

4.0 × 10⁵

0/16

-

CGL003

Jackson-Pratt fluid

32

0.5

5.4 × 10⁵

8/16

-

C. dubliniensis

18S

Saliva

16

0.25

3.9 × 10⁵

16/16

18

155S

Saliva

0.5

0.25

5.1 × 10⁵

16/16

18

C. lusitaniae

CLU005

Blood culture

2

1

1.4 × 10⁵

14/16

-

C.norvegensis

52S

Saliva

32

0.5

6.3 × 10⁵

6/16

-

C. krusei

58

OPC

Resistant

2

8.8 × 10⁵

4/16

-

C. kefyr

CKE002

Blood culture

2

1

4.2 × 10⁵

2/16

-