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Table 1 Peptide Cleavage Products for BoNT/B and/G.

From: A historical and proteomic analysis of botulinum neurotoxin type/G

 

BoNT/B and/G Substrate

Masses

Intact

LSELDDRADALQAGASQFESAAKLKRKYWWKNLK

4025

/B-NT

LSELDDRADALQAGASQ

 

1759

/B-CT

 

FESAAKLKRKYWWKNLK

2283

/G-NT

LSELDDRADALQAGASQFESA

 

2281

/G-CT

 

AKLKRKYWWKNLK

1762

  1. The predicted cleavage products and the masses of the substrate and product peptides for both/B and/G are shown. The substrate peptide was derived from the human Synaptobrevin-2 (VAMP-2) protein. Note that/B and/G cleave 4 amino acids apart.