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Table 2 Antimicrobial resistance gene products encoded by A.baumannii genomes

From: Genome organization of epidemic Acinetobacter baumanniistrains

Gene Products

   

Strains

   
 

AB0057

AYE

3990

ACICU

4190

ATCC17978

3909

Class C β-lactamase

9, 2796

1110

2437

2564

2076

2367

1404

Class A β-lactamase

283 (TEM-1)

-

-

-

-

-

-

 

-

3623 (VEB-1)

-

-

-

-

-

Class D β-lactamase

1757 (oxa-69)

2122 (oxa-69)

2827 (oxa-66)

1560 (oxa-66)

63 (oxa-64)

1517 (oxa-95)

1089 (oxa-90)

 

-

-

3514 (oxa-20)

0226 (oxa-20)

-

-

-

 

0551 (oxa-23)*

-

-

-

-

-

-

 

-

-

p2ABST2 (oxa-58)*

pACICU1

(oxa-58)* (2X)

p1ABST25 (oxa-72)*

-

p1ABST78 (oxa-58)*

 

-

-

-

-

p2ABST25 (oxa-72)*

-

-

AAC (3)-I aminoglycoside acetyltransferase

291

3573

-

-

-

-

-

AAC (6')-I aminoglycoside acetyltransferase

-

3630

3516

223

-

-

-

APH (3')-I aminoglycoside phosphotransferase

288

3578

-

-

-

-

-

 

-

-

3897

1948

560

-

-

ANT (3'')-I aminoglycoside adenylyltransferase

293

3570,3618

-

-

3268

-

-

 

171

3739

1641

156

2954

131

2919

Chloramphenicol acetyl transferase

280

3587

-

-

-

-

-

 

3104

798

3709

2932

1731

2691

1443

DNA topoisomerase II

3037 [R1]

0867 [R1]

0747 [R1]

2869 [R1]

2907 [R1]

2626 [S]

0539 [R1]

DNA topoisomerase IV

0232 [R2]

3679 [R2]

1415 [S]

0214 [S]

2382 [R2]

-

3413 [R2]

RNA polymerase β Subunit

0369 [S]

3489 [S]

2179 [R3]

0303 [S]

3155 [S]

0287 [S]

0411 [S]

Dihydropteroate synthase

265, 294

3568,3616,3612

3142

228

-

675

-

 

3095

807

3700

2923

2684

2680

1433

Dihydrofolate reductase type 1

-

3644

-

-

-

-

-

Dihydrofolate reductase type 3

540

3315

3351

467

3501

457

403

  1. R, resistant; S, susceptible; R1 81 Ser →Leu; R2 84 Ser → Leu; R 3 535 His → Leu; * carbapenem-hydrolysing class D beta-lactamase; + ORFs identified by tBLASTn.