Table 2 P. aeruginosa genes with decreased expression at pH 7.5 vs pH 6.0

PA5170

arcD

-1.91

Arginine/ornithine antiporter ArcD

   Arginine deiminase pathway

PA5171

arcA

-4.3

Arginine deiminase (EC 3.5.3.6)

   Arginine deiminase pathway

PA5172

arcB

-2.82

Ornithine carbamoyltransferase (EC 2.1.3.3)

   Arginine deiminase pathway

PA5173

arcC

-2.13

Carbamate kinase (EC 2.7.2.2)

   Arginine deiminase pathway

PA0530

-2.49

Acetylornithine aminotransferase (EC 2.6.1.11)

   Arginine_Biosynthesis_extended

PA3865

-2.74

Arginine/ornithine ABC transporter, periplasmic arginine/ornithine binding protein

   Arginine deiminase pathway

PA1540

-2.14

Spermidine export protein mdtI

   Small_Multidrug_Resistance

PA1541

-3.44

Spermidine export protein mdtJ

   Small_Multidrug_Resistance

PA0509

nirN

-3.39

Nitrite reductase associated c-type cytochorome NirN

   Dissimilatory_nitrite_reductase

PA0510

-4.39

Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)

   Dissimilatory_nitrite_reductase

PA0511

nirJ

-5.67

Heme d1 biosynthesis protein NirJ

   Dissimilatory_nitrite_reductase

PA0512

-1.84

Heme d1 biosynthesis protein NirH

   Dissimilatory_nitrite_reductase

PA0513

-1.76

Heme d1 biosynthesis protein NirG

   Dissimilatory_nitrite_reductase

PA0514

nirL

-2.32

Heme d1 biosynthesis protein NirL

   Dissimilatory_nitrite_reductase

PA0515

-7.33

Heme d1 biosynthesis protein NirD

   Dissimilatory_nitrite_reductase

PA0516

nirF

-2.59

Heme d1 biosynthesis protein NirF

   Dissimilatory_nitrite_reductase

PA0517

nirC

-7.03

Cytochrome c55X precursor NirC

   Dissimilatory_nitrite_reductase

PA0518

nirM

-10.01

Cytochrome c551 NirM

   Dissimilatory_nitrite_reductase

PA0519

nirS

-8.9

Cytochrome cd1 nitrite reductase (EC:1.7.2.1)

   Denitrification

PA0520

nirQ

-2.02

Nitric oxide reductase activation protein NorQ

   Denitrification

PA0521

-1.91

Nitric oxide reductase activation protein NorE

   Denitrification

PA0523

norC

-8.51

Nitric-oxide reductase subunit C (EC 1.7.99.7)

   Denitrification

PA0524

norB

-9.78

Nitric-oxide reductase subunit B (EC 1.7.99.7)

   Denitrification

PA0525

-3.39

Nitric oxide reductase activation protein NorD

   Denitrification

PA1172

napC

-1.51

Cytochrome c-type protein NapC

   Nitrate_and_nitrite_ammonification

PA1173

napB

-2.01

Nitrate reductase cytochrome c550-type subunit

   Nitrate_and_nitrite_ammonification

PA1174

napA

-2.01

Periplasmic nitrate reductase precursor (EC 1.7.99.4)

   Nitrate_and_nitrite_ammonification

PA2662

-1.90

NnrS protein involved in response to NO

   Denitrification

PA3391

nosR

-2.17

Nitrous oxide reductase maturation protein NosR

   Denitrification

PA3392

nosZ

-3.16

Nitrous-oxide reductase (EC 1.7.99.6)

   Denitrification

PA3393

nosD

-1.40

Nitrous oxide reductase maturation protein NosD

   Denitrification

PA2826

-5.48

Glutathione peroxidase family protein

   Stress response

PA2850

-2.28

Organic hydroperoxide resistance protein

   Stress response

PA3017

-1.56

Universal stress protein UspA and related nucleotide-binding proteins

   Stress response

PA3309

-3.47

Universal stress protein UspA and related nucleotide-binding proteins

   Stress response

PA4352

-7.28

Universal stress protein UspA and related nucleotide-binding proteins

   Stress response

PA5027

-4.50

Universal stress protein UspA and related nucleotide-binding proteins

   Stress response

PA4760

dnaJ

-2.02

Chaperone protein DnaJ

   Stress response

PA4761

dnaK

-2.41

Chaperone protein DnaK

   Stress response

PA4762

grpE

-2.70

Heat shock protein GrpE

   Stress response

PA4587

ccpR

-12.82

Cytochrome c551 peroxidase (EC 1.11.1.5)

   Stress response

PA4206

-3.50

Probable Co/Zn/Cd efflux system membrane fusion protein

   Resistance

PA4207

-3.52

RND multidrug efflux transporter; Acriflavin resistance protein

   Resistance

PA4208

-3.52

Probable outer membrane efflux protein precursor

   Resistance