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Table 1 Latent variables related to specific adaptation

From: Bacterial adaptation during chronic infection revealed by independent component analysis of transcriptomic data

Latent variables

Related strains

Functions of selected enriched genes by ICA

  

Up regulated

Down regulated

2

B12-4, B12-7

Antibiotic resistance

Iron metabolism

Citronellol/leucine catabolism

-

4

B6-0, B6-4

LPS modification

Flagellum biogenesis

16

CF114-1973

Fimbrial biogenesis

-

20

CF66-2008

LPS modification

-

22

CF173-2002

-

-

14

Early stage isolates from 1973

Type III secretion

-

6

Late stage isolates

Antimicrobial peptide tolerance

-

10

Late stage isolates

Potassium uptake system

Quorum sensing

18

Late stage isolates

Alginate biosynthesis

Motilities