Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 4 | BMC Microbiology

Figure 4

From: Specific antibody-receptor interactions trigger InlAB-independent uptake of listeria monocytogenes into tumor cell lines

Figure 4

Effect of serum incubation on antibody-mediated internalization of Lm-spa+. The bacteria were incubated with PBS (-mAb), Cetuximab or Trastuzumab and the antibodies were covalently bound to protein A by crosslinking with DMP. Subsequently the bacteria were incubated with murine serum prior to infection of 4T1-HER2 cells. Intracellular CFU was determined after gentamicin treatment by plating serial dilutions. The relative internalization rate in comparison to uncoated bacteria was calculated and is shown.

Back to article page