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Table 2 Comparison of amino acid sequence at G-H loop of VP1 of the viruses derived from different origins and full-length plasmids

From: In-vitro and in-vivo phenotype of type Asia 1 foot-and-mouth disease viruses utilizing two non-RGD receptor recognition sites

Virus/plasmid Encoded G-H loop amino acid sequencec Additional amino acid changes in VP1
Asia1/JS/CHA/05 TTYGEESSRRGDLAALARRVNNRLPTS -
Asia1/JSp1 TTYGEESSRRGDLAALARRVNNRLPTS -
Asia1/JSp1c4 TTYGEESSRRDDLAALARRVSNRLPTS N154S
Asia1/JSp1c8 TTYGEESSRRDDLAALARRVSNRLPTS N154S
Asia1/JSp1c20 TTYGEESSRRDDLAALARRVSNRLPTS N154S
Asia1/JSM4 TTYGEESSRRGDLAALARRVNNRLPTS -
  TTYGEESSRRSDLAALARRVNNRLPTS -
Asia1/JSM6c20 TTYGEESSRRGDLAALARRVNNRLPTS -
  TTYGEESSRRSDLAALARRVNNRLPTS -
pRDD TTYGEESSRRDDLAALARRVSNRLPTS -
pRSD TTYGEESSRRSDLAALARRVSNRLPTS -
pRGD TTYGEESSRRGDLAALARRVSNRLPTS -
FMDV-RDDa TTYGEESSRRDDFAALARRVSNRLPTS L146F
FMDV-RSDa TTYGEESSRRSDLAALARRVSNRLPTS N154S
FMDV-RGDa TTYGEESSRRGDFAALARRVSNRLPTS L146F
FMDV-RDD/pigb TTYGEESSRRDDLAALARRVSNRLPTS -
FMFV-RDD/bovineb TTYGEESSRRDDLAALARRVSNRLPTS -
FMDV-RSD/pigb TTYGEESSRRSDLAALARRVSNRLPTS -
FMDV-RSD/bovineb TTYGEESSRRSDLAALARRVSNRLPTS -
  1. aThe rescued viruses were passaged 20 times in cell culture.
  2. bVirus recovered from vesicular lesions, away from the inoculation site.
  3. cSequence data were obtained by RT-PCR of the VP1 capsid region. The dashes represent receptor binding triplet of the viruses derived from different origins and full-length plasmids.