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Figure 4 | BMC Microbiology

Figure 4

From: Transcriptomic analysis of Clostridium thermocellumATCC 27405 cellulose fermentation

Figure 4

Expression of genes involved in cellodextrin transport and catabolism during cellulose fermentation. Schematic representation of cellulose degradation by cell surface attached cellulosomal complex, transport of cellodextrin hydrolysis products into the cell by ABC sugar transporters and intracellular catabolism of glucose to various metabolic end-products. Heat plot representation of transcript expression [as Log2 (array signal intensity)] for genes (known and putative) involved in cellodextrin transport and hydrolysis, pentose phosphate pathway, glycolytic conversion of glucose to pyruvate and anaerobic fermentation of pyruvate to organic acids (formate, lactate, acetate) and ethanol, over the course of Avicel® fermentation by Clostridium thermocellum ATCC 27405. Cellulosome schematic is an adaptation of the image from the U.S. Department of Energy Genome Programs website image gallery (http://genomics.energy.gov; [40]);one black circle- Cthe0506 is pfl-activating enzyme; two black circles- Cthe0423 encodes a bi-functional acetaldehyde/alcohol dehydrogenase enzyme involved in direct conversion of acetyl-CoA to ethanol; open diamond- Microarray data is not available.

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