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Table 5 Intermonomer interactions for alanine racemases from Gram-positive bacteria calculated using PISA [69] and PROTORP [70]

From: The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design

 

Buried surface area (Å2)

H-bonds

Salt link

# residues

% interface residues

 

Monomer A

Monomer B

  

A

B

polar

non-polar

charged

AlrSP

3035

3020

33

10

91

91

30

47

22

AlrGS

3058

3109

43

17

89

88

27

43

30

AlrSL

2800

2799

26

6

87

87

39

43

18

AlrBA

3529

3529

45

10

93

95

28

44

27

AlrEF

2936

2936

38

12

86

86

32

41

28