Figure 2

Anti-biofilm activity of peptides. Inhibition of S. aureus biofilm formation was demonstrated for each of the following peptides. A. NA-CATH. B. NA-CATH:ATRA1-ATRA1. C. LL-37. D. D-LL-37. E. Scrambled LL-37. Growth (absorbance at 600 nm) is indicated by gray bars with "0 peptide" control set to 100%. Biofilm detection on a polystyrene 96-well plate at 37°C after 24 h of growth in TSB was detected as the absorbance of crystal violet stain (570 nm). Percent biofilm production is indicated by black bars (n = 6), relative to "0 peptide" control. Each experiment is a representative of at least two independent trials. Error bars indicate the standard deviation from the mean. The asterisk (*) indicates statistically different than the positive control (p < 0.01).