Skip to main content

Table 1 Burkholderia isolates used in this study.

From: Macrophage and Galleria mellonella infection models reflect the virulence of naturally occurring isolates of B. pseudomallei, B. thailandensis and B. oklahomensis

Isolate Description and reference MIC (μg/ml kanamycin) Virulence in mice by i.p. route
B. pseudomallei    
K96243 Clinical isolate from Thailand, sequenced strain [26] 128 MLD = 262 (i.p.) [7]
576 Clinical isolate from Thailand [28] 128 MLD = 80 (i.p.) [7]
708a Gentamicin-sensitive isolate from Thailand [9] 16 MLD = 2.3 × 103 (i.p.) [7]
B. thailandensis    
E264 Environmental isolate, sequenced strain [10, 37] 128 1/10 survivors at 107 cfu [16]
Phuket 4W-1 Water isolate from Thailand [38] 128 2/10 survivors at 107 cfu [16]
CDC3015869 Clinical isolate from Texas; abbreviated as CDC301 [39] 128 8/10 survivors at 107 cfu [16]
CDC2721121 Clinical isolate from Louisiana; abbreviated as CDC272 [39] 128 10/10 survivors at 107 cfu [16]
B. oklahomensis    
C6786 Clinical isolate from Oklahoma [40] 128 10/10 survivors at 107 cfu [16]
E0147 Clinical isolate from Georgia [41] 128 10/10 survivors at 107 cfu [16]
  1. Description of the Burkholderia strains used in this study, their susceptibility to kanamycin as described by the minimum inhibitory concentration (MIC) and a summary of published data on virulence of these isolates in mice described as the median lethal dose (MLD) in colony forming units or as number of survivors.