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Table 4 Predictive values at cut-off values 0.400 and 0.200

From: Evaluation of the hyplex® TBC PCR test for detection of Mycobacterium tuberculosis complex in clinical samples

 

cut-off 0.400

cut-off 0.200

 

PCR posb

PCR negb

TOTAL a

PCR posb

PCR negb

TOTAL a

TB pos (n)

199

41

240

221

19

240

TB neg (n)

21

2739

2760

414

2346

2760

TOTAL (n)

220

2780

3000

635

2365

3000

PPVc (%)

90.4

34.8

NPVc (%)

98.5

99.1

  1. a Based on the assumption of a mean rate of 8.0% true TB positive specimens and a total number of 3000 specimens in a routine TB laboratory per year, the resulting numbers of TB positive and negative samples were calculated.
  2. b Based on the specificity and sensitivity values found in this study, the numbers of expected PCR positive and negative results among 3000 were calculated. Resulting numerical values were rounded.
  3. c Positive and negative predictive values were deduced from calculated PCR positive and negative results.