Melanin in Fonsecaea pedrosoi: a trap for oxidative radicals

BMC Microbiology

Table 1 Nitrite concentration after fungal interaction with activated murine macrophages.

	Nitrite concentration (μM)*
Activated murine macrophages	After 24 h	After 48 h
Without fungus	20.0 ± 0.70	50.0 ± 0.70
With *F. pedrosoi*	1.9 ± 0.40	4.0 ± 0.28
With 1 μg/ml of melanin isolated from *F. pedrosoi*	0.9 ± 0.54	1.1 ± 0.14
With TC-treated *F. pedrosoi*	36.2 ± 1.25	50.0 ± 3.95

*Mean values ± standard deviation recorded after 3 independent experiments.
Molar concentration of nitrite detected after interaction of F. pedrosoi or melanin from F. pedrosoi with activated murine macrophages for 24 and 48 h.

ISSN: 1471-2180