Figure 3
From: Binding and activation of host plasminogen on the surface of Francisella tularensis
εACA inhibits huPLG binding to FT in a dose-dependent fashion. FTLVS was coated onto microtiter plate wells and incubated for 2 hours with purified huPLG (3 μg/mL) in the presence or absence of titrated concentrations of εACA. The results shown are representative of 3 experiments of similar design. Bars indicate +/- SEM in triplicate. Statistical analysis performed via one-way ANOVA using a Kruskal-Wallis test determined a p-value of < 0.0001.