Skip to main content

Table 2 Level of rifampicin resistance and mutations found in the rpoB gene of MRSA isolates and control strains

From: Molecular characterization of resistance to Rifampicin in an emerging hospital-associated Methicillin-resistant Staphylococcus aureus clone ST228, Spain

Genotype
(ST/SCCmec/PFGE)
Rifampicin MICs
(mg/L)
Number of isolates Nucleotide mutation Amino acid substitution
ST228/IV-A/A 0.012 5 None  
ST228/I/B 2-4 28 C AT→A AT 481His→Asn
ST228/I/B 128 2 C AT→A AT
G CT→A CT
481His→Asn
477Ala→Thr
ST228/I/B 256 1 C AT→A AT
C AA→A AA
481His→Asn
468Gln→Lys
ST228/I/B 256 1 C AT→A AT
A TT→C TT
481His→Asn
527Ile→Leu
ST247/I
PER88
(Iberian clone)
256 1 C AT→A AT
TCA→TTA
481His→Asn
529Ser→Leu
ST247/I
ATCCBAA44
(Iberian clone)
2 1 C AT→A AT 481His→Asn