Serotype- and strain- dependent contribution of the sensor kinase CovS of the CovRS two-component system to Streptococcus pyogenes pathogenesis

Table 1 Capsular hyaluronic acid measurements.

Strains	Capsule-associated hyaluronic acid (fg/CFU)
M49	14.0 ± 1.5
M49::covS	38.6 ± 3.6
M18	87.2 ± 0.2
M18::covS	114.7 ± 3.7
M2	15.5 ± 3.6
M2::covS	30.6 ± 3.3
M6	15.5 ± 1.7
M6::covS	23.9 ± 0.2

Hyaluronic acid amounts produced by the GAS strains used was determined as described previously [27] and was expressed as fg of hyaluronic acid per CFU.

ISSN: 1471-2180