Table 5 Target pathway of up-regulated Genes in SL1344 vs SB1117 infection groups at 8 hours.
Ingenuity Canonical Pathways | Up-regulated | Molecules |
|---|---|---|
Cholecystokinin/Gastrin mediated Signaling | 8/104 (8%) | FOS, RHOV, JUN, RHOB, RHOD, IL1RN, RHOC, IL1F8 |
MIF Regulation of Innate Immunity | 3/46 (7%) | FOS, LY96, JUN |
Complement System | 2/36 (6%) | C3, C1S |
FAK Signaling | 6/98 (6%) | CAPN5, ARHGAP26, CAPN9, CAPN2, ITGA3, ACTC1 |
HMGB1 Signaling | 6/98 (6%) | FOS, RHOV, JUN, RHOB, RHOD, RHOC |
IL-10 Signaling | 4/70 (6%) | FOS, JUN, IL1RN, IL1F8 |
Integrin | 111/200(6%) | CAPN5, RHOV, ARHGAP26, RHOB, RHOD, ITGA11, RHOC, CAPN9, CAPN2, ITGA3, ACTC1 |
| Â | 7/112 (6%) | PLCZ1, RHOV, RHOB, RHOD, RHOC, PLCL2, CASP14 |
Toll-like Receptor Signaling | 3/54 (6%) | FOS, LY96, JUN |
B Cell A ctivating Factor Signaling | 2/44 (5%) | FOS, JUN |
Coagulation System | 2/37 (5%) | FGA, F3 |
CXCR4 Signaling | 8/168 (5%) | FOS, RHOV, JUN, RHOB, RHOD, RHOC, EGR1, GNG5 |
IL-2 Signaling | 3/58 (5%) | FOS, JUN, SYK |
ILK Signaling | 10/187(5%) | MUC1, FOS, RHOV, JUN, RHOB, RHOD, RHOC, PPM1J, ACTC1, IRS3 |
Phototransduction Pathway | 3/65 (5%) | OPN3, GRK1, PDE6H |
Production of Nitric Oxide and reactive Oxygen Species in Macrophages | 10/185 (5%) | FOS, RHOV, JUN, RHOB, PPP1R14 D, RHOD, RHOC, PPM1J, HOXA10, SPI1 |
Regulation o f Actin based | 5/93 (5%) | RHOV, RHOB, RHOD, |
Motility by Rho | Â | RHOC, ACTC1 |
Role of Cytokines in Mediating Communication between Immune Cells | 3/57 (5%) | IL1RN, IFNA5, IL1F8 |
Role of Pattern Recognition Receptors in Recognition of Bacteria and Viruses | 4/86 (5%) | IRF4, C3, SYK, IFNA5 |
| Â | 4/114 (4%) | PLCZ1, FOS, JUN, PLCL2 |